Karuizawa distillery 軽井沢蒸溜所 was a Japanese whisky distillery. It was located at Miyota, a town on the southern slopes of an active complex volcano, Mount Asama, in Nagano Prefecture, Japan.

Established in 1955, the distillery began production in 1956. It was owned by Mercian Corporation and was the smallest in Japan. It was mothballed in 2000, and closed in 2011, The remaining whiskey stock from the distillery was purchased and re-branded, then released as a series of luxury whiskies.

A rare single cask Karuizawa bottled in 2016 at cask strength. Distilled in 1994 and fully matured in sherry cask #4019